Venkatachalam Thiruppugazh: Natural Disasters and their Mitigation in South Asia. And we are investigating the basic mechanisms of intracellular calcium handling in cardiac and skeletal muscle to further understand the paradigms of excitation-transcription coupling and excitation-signaling coupling. Doron is currently working on questions to do with public health. We study the cardiac fibroblast and how it functions during disease to alter the extracellular matrix, which affects heart remodeling. Our laboratory is also actively engaged in identifying novel secreted protein factors in the heart (cytokines, growth factors, chemokines) that might control disease responsiveness. Similarly, we are examining the transcriptional regulatory factors and epigenetic mechanisms that regulate cardiac and skeletal muscle differentiation, growth, death and replication, in order to suggest additional targets for treating human disease. A better understanding of the signaling pathways that control these processes, coupled with the identification of novel genes, could suggest new treatment strategies for human diseases. We are also interested in characterizing the intracellular signaling pathways that control cellular growth, differentiation and replication in cardiac and skeletal muscle. Studies Cardiovascular research, Cardiology Cardiac Hypertrophy, and Embryonic Stem Cells. Prominent diseases of both heart and skeletal muscle are affected by cellular necrosis, so identifying the genes that control this process could have a substantial effect on our treatment of these types of diseases. muthai tharu pathi lyrics thiruppugazh lyrics in tamil muthai tharu thiruppugazh lyrics thirupugal lyrics thirupugal. Thirupugal Govindarajan, National Institutes of Health, Cardiovascular Research Department, Post-Doc. Involved in viral clearance studies & assays development (molecular and tissue culture-based) for the detection of retro and adventitious viruses from recombinant protein products expressed in mammalian systems and from other biological.

Toward this end we study the basic machinery that underlies cell death, with a special interest in mitochondrial-dependent mechanisms of nonapoptotic death (such as cellular necrosis). Working in a GLP certified & compliant facility. Our laboratory investigates a range of focus areas, all of which center on understanding the molecular mechanisms of heart and skeletal muscle disease.

Read ' New Leaders in Cardiovascular Science' in Circulation Research featuring Dr.

Thirupugal for health